How Long Does a Sickle Cell Live?

Sickle Cell As a Disability

If you’re wondering, “How long does a sickle cell live?”, you’re not alone. In this article, we’ll cover Symptoms and Treatment, as well as Genetic testing. Also, we’ll touch on Genetic testing. If you have sickle cell disease, life expectancy is approximately 10 to 20 years. A person with sickle cell disease can experience tiredness and anemia. Symptoms of sickle cell disease include fatigue, anemia, and frequent headaches.

Life expectancy

The life expectancy of sickle cell anemia has risen dramatically in the last 30 years, with the introduction of hydroxyurea and prophylactic penicillin V. In 1980, Hebbel et al. first identified the existence of abnormally adhesive sickle red blood cells. Further studies found that other blood cells may also be activated in sickle cell disease and contribute to vaso-occlusive crises.

Previously, SCD was lethal in childhood, but today, life expectancy is significantly higher in Europe and North America. In Paris and London, the life expectancy of an adult with the disease is 97 percent, while the U.S.’s life expectancy is about 94 percent. Despite this, people with sickle cell disease are still far shorter-lived than the general population. In the meantime, however, advances in treatment and research continue to improve survival rates.

In the study, 50 percent of people with sickle cell anemia lived past their fifth decade. But a significant portion of patients died at an early age, and not from chronic organ failure. A large proportion died during an acute episode of chest syndrome, pain, or a stroke. Early mortality was highest in the symptomatic population. One interesting factor to note is that high fetal hemoglobin levels were associated with improved survival and are likely a reliable predictor of adult life expectancy.


The primary endpoint of this study was the number of episodes of pain related to sickle cell disease. High-dose therapy was compared to placebo. This study also found that the treatment reduced the number of pain crises, but there were side effects. Patients should consult a doctor for a full list of side effects. In some cases, the condition can cause severe pain, and a sickle cell crisis can cause a stroke.

When the sickle cells pool in the spleen, they cause a condition known as a sickle cell crisis. The patient experiences a severe drop in hemoglobin and is extremely tired. They may also experience enlarged spleens. These symptoms can make life uncomfortable for the patient and may require hospitalization. Acute chest syndrome can result in a fever of more than 101 degrees Fahrenheit, and may cause scarring and permanent damage to the body. In addition to the pain, male patients with sickle cell disease may experience painful erections.


When your child develops sickle cell disease, they may experience pain on the lower third of the leg, around the ankle bones. It may take months for the pain to go away, and you should seek medical attention if it is severe. Pain can also be caused by infection and inflammation. In addition, your child may experience fever and difficulty breathing. In addition to painful skin lesions, sickle cell disease can cause jaundice.

Acute chest syndrome can also be an early symptom. This condition causes blood vessels in the lungs to become enlarged. It can also cause serious damage to the brain. It can cause seizures, numbness, loss of consciousness, and abdominal pain. Severe episodes can even lead to death. Other symptoms may be more subtle. Acute chest syndrome (ACH), caused by sickle cells, is an emergency situation and may require immediate medical attention.

Genetic testing

A family history of sickle cell disease is a risk factor for sickle cell disease, which is passed down through genetics. Children born to parents who carry the sickle cell trait have a 50% chance of developing sickle cell disease. Genetic testing can determine whether your child is a carrier. In some cases, it may even be possible to conceive a child without sickle cell disease by performing a PGT (preimplantation genetic testing) test.

Although newborn screening is not diagnostic, it can identify a baby who is at risk of developing sickle cell disease. A blood test using hemoglobin electrophoresis can determine whether your child has the sickle cell trait. This test looks for disease-causing mutations in the HBB gene. If your child has two or more of these mutations, he or she will have sickle cell disease. This disease is chronic and requires ongoing monitoring and management by a medical specialist.

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